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t(6;6)(q22;q22) GOPC/ROS1

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)


Atlas_Id 6783
Phylum Lung::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

Clinics and Pathology

Disease Lung:Lung, Heart, Skin, Other: Lung: Non-small cell carcinoma: Adenocarcinoma: t(6;6)(q22;q22) GOPC/ROS1

Genes involved and Proteins

Gene NameGOPC
Location 6q22.1

Gene NameROS1
Location 3q11.1


Identification of KIF5B-RET and GOPC-ROS1 fusions in lung adenocarcinomas through a comprehensive mRNA-based screen for tyrosine kinase fusions
Suehara Y, Arcila M, Wang L, Hasanovic A, Ang D, Ito T, Kimura Y, Drilon A, Guha U, Rusch V, Kris MG, Zakowski MF, Rizvi N, Khanin R, Ladanyi M
Clin Cancer Res 2012 Dec 15;18(24):6599-608
PMID 23052255

Translocations implicated (Data extracted from papers in the Atlas)

 t(6;6)(q22;q22) GOPC/ROS1

External links

Mitelman database t(6;6)(q22;q22) [CaseList]    t(6;6)(q22;q22) [Transloc - MCList] GOPC/ROS1 [Fusion - MCList]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(6;6)(q22;q22) GOPC/ROS1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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indexed on : Fri Mar 9 17:58:32 CET 2018

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