Atlas of Genetics and Cytogenetics in Oncology and Haematology

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t(6;7)(p21;p15) JAZF1/PHF1

(Note : for Links provided by Atlas : click)


Atlas_Id 107316
Phylum Female organs: Uterus::
WHO/OMS Classification Female organs
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Uterus: Endometrial stromal sarcoma

Genes involved and Proteins

Gene NameJAZF1
Location 7p15.2

Gene NamePHF1
Location 6p21.32


Consistent rearrangement of chromosomal band 6p21 with generation of fusion genes JAZF1/PHF1 and EPC1/PHF1 in endometrial stromal sarcoma
Micci F, Panagopoulos I, Bjerkehagen B, Heim S
Cancer Res 2006 Jan 1;66(1):107-12
PMID 16397222
An endometrial stromal sarcoma cell line with the JAZF1/PHF1 chimera
Panagopoulos I, Mertens F, Griffin CA
Cancer Genet Cytogenet 2008 Sep;185(2):74-7
PMID 18722875

Translocations implicated (Data extracted from papers in the Atlas)

 t(6;7)(p21;p15) JAZF1/PHF1

External links

Mitelman database t(6;7)(p21;p15) [CaseList]     t(6;7)(p21;p15) [Transloc - MCList]   JAZF1/PHF1 Fusion - MCList]
COSMIC[ JAZF1 ]   [ PHF1 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(6;7)(p21;p15) JAZF1/PHF1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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indexed on : Sat Dec 5 18:54:20 CET 2020

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