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t(6;9)(q24;p22) NFIB/AIG1

Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 107356
Phylum Head and Neck: Salivary gland::
WHO/OMS Classification Head and Neck
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Salivary gland: Adenoid cystic carcinoma

Genes involved and Proteins

Gene NameNFIB
Location 9p23

Gene NameAIG1
Location 6q24.2

Bibliography

Novel chromosomal rearrangements and break points at the t(6;9) in salivary adenoid cystic carcinoma: association with MYB-NFIB chimeric fusion, MYB expression, and clinical outcome
Mitani Y, Rao PH, Futreal PA, Roberts DB, Stephens PJ, Zhao YJ, Zhang L, Mitani M, Weber RS, Lippman SM, Caulin C, El-Naggar AK
Clin Cancer Res 2011 Nov 15;17(22):7003-14
PMID 21976542
 
Novel MYBL1 Gene Rearrangements with Recurrent MYBL1-NFIB Fusions in Salivary Adenoid Cystic Carcinomas Lacking t(6;9) Translocations
Mitani Y, Liu B, Rao PH, Borra VJ, Zafereo M, Weber RS, Kies M, Lozano G, Futreal PA, Caulin C, El-Naggar AK
Clin Cancer Res 2016 Feb 1;22(3):725-33
PMID 26631609
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(6;9)(q24;p22) NFIB/AIG1

External links

Mitelman database t(6;9)(q24;p22) [CaseList]     t(6;9)(q24;p22) [Transloc - MCList]   NFIB/AIG1 Fusion - MCList]
COSMIC[ NFIB ]   [ AIG1 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(6;9)(q24;p22) NFIB/AIG1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Wed Nov 28 16:43:02 CET 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.