Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

t(6;10)(p22;q11) TRIM27/RET

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)


Atlas_Id 113314
Phylum Neuro-Endocrine/Endocrine system: Thyroid::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

Clinics and Pathology

Disease Neuro-Endocrine/Endocrine system: Thyroid:Adenocarcinoma

Genes involved and Proteins

Gene NameTRIM27
Location 6p22.1

Gene NameRET
Location 10q11.21


Novel tumorigenic rearrangement, Delta rfp/ret, in a papillary thyroid carcinoma from externally irradiated patient
Saenko V, Rogounovitch T, Shimizu-Yoshida Y, Abrosimov A, Lushnikov E, Roumiantsev P, Matsumoto N, Nakashima M, Meirmanov S, Ohtsuru A, Namba H, Tsyb A, Yamashita S
Mutat Res 2003 Jun 19;527(1-2):81-90
PMID 12787916
The landscape of kinase fusions in cancer
Stransky N, Cerami E, Schalm S, Kim JL, Lengauer C
Nat Commun 2014 Sep 10;5:4846
PMID 25204415
Integrated genomic characterization of papillary thyroid carcinoma
Cancer Genome Atlas Research Network
Cell 2014 Oct 23;159(3):676-90
PMID 25417114

Translocations implicated (Data extracted from papers in the Atlas)

 t(6;10)(p22;q11) TRIM27/RET

External links

Mitelman database t(6;10)(p22;q11) [CaseList]    t(6;10)(p22;q11) [Transloc - MCList] TRIM27/RET [Fusion - MCList]
COSMIC[ TRIM27 ]   [ RET ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(6;10)(p22;q11) TRIM27/RET
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Feb 23 20:39:35 CET 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us