Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

t(6;10)(q22;q25) SHTN1/ROS1

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 108305
Phylum Lung, Heart, Skin, Other: Skin::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Lung, Heart, Skin, Other: Skin:Melanocytic neoplasm, special type

Genes involved and Proteins

Gene NameSHTN1
Location 10q25.3

Gene NameROS1
Location 3q11.1

Bibliography

Kinase fusions are frequent in Spitz tumours and spitzoid melanomas
Wiesner T, He J, Yelensky R, Esteve-Puig R, Botton T, Yeh I, Lipson D, Otto G, Brennan K, Murali R, Garrido M, Miller VA, Ross JS, Berger MF, Sparatta A, Palmedo G, Cerroni L, Busam KJ, Kutzner H, Cronin MT, Stephens PJ, Bastian BC
Nat Commun 2014;5:3116
PMID 24445538
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(6;10)(q22;q25) SHTN1/ROS1

External links

Mitelman database t(6;10)(q22;q25) [CaseList]     t(6;10)(q22;q25) [Transloc - MCList]   SHTN1/ROS1 Fusion - MCList]
COSMIC[ SHTN1 ]   [ ROS1 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(6;10)(q22;q25) SHTN1/ROS1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 22 18:00:27 CEST 2018


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.