t(6;11)(p21;q13) SRF/RELA

0000-00-00   Jean-Loup Huret , Philippe Dessen 

(Note: the fusion was discovered by NGS. Many chromosome rearrangement mechanisms such as translocation, inversion,deletion or complex rearrangement may lead to the same fusion)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute

Summary

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Genes Involved and Proteins

Gene name

Location

6p21.1

Gene name

Location

11q13.1

Highly cited references

Pubmed IDYearTitleCitations
282488152017Recurrent SRF-RELA Fusions Define a Novel Subset of Cellular Myofibroma/Myopericytoma: A Potential Diagnostic Pitfall With Sarcomas With Myogenic Differentiation.11
330215232020SRF Fusions Other Than With RELA Expand the Molecular Definition of SRF-fused Perivascular Tumors.3
314789432020Novel SRF-ICA1L Fusions in Cellular Myoid Neoplasms With Potential For Malignant Behavior.1
358521782022Uterine tumours with myogenic differentiation harbouring SRF::RELA fusions.0
317386352021Myofibromatosis.0
325293512021Genetic variant of SRF-rearranged myofibroma with a misleading nuclear expression of STAT6 and STAT6 involvement as 3' fusion partner.0
317051902020What is new in pericytomatous, myoid, and myofibroblastic tumors?0

Bibliography

Pubmed IDLast YearTitleAuthors
282488152017Recurrent SRF-RELA Fusions Define a Novel Subset of Cellular Myofibroma/Myopericytoma: A Potential Diagnostic Pitfall With Sarcomas With Myogenic Differentiation.Antonescu CR et al

Citation

Jean-Loup Huret ; Philippe Dessen

t(6;11)(p21;q13) SRF/RELA

Atlas Genet Cytogenet Oncol Haematol. 0000-00-00

Online version: http://atlasgeneticsoncology.org/solid-tumor/106866/t(6;11)(p21;q13)-srf-rela