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t(6;12)(p21;q15) MDM2/RUNX2

Written2018-01Jean-Loup Huret, Philippe Dessen

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Atlas_Id 112769
Phylum Bones::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

Clinics and Pathology

Disease Bones:Osteosarcoma, NOS

Genes involved and Proteins

Gene NameMDM2
Location 12q15

Gene NameRUNX2


Recurrent LRP1-SNRNP25 and KCNMB4-CCND3 fusion genes promote tumor cell motility in human osteosarcoma
Yang J, Annala M, Ji P, Wang G, Zheng H, Codgell D, Du X, Fang Z, Sun B, Nykter M, Chen K, Zhang W
J Hematol Oncol 2014 Oct 10;7:76
PMID 25300797

Translocations implicated (Data extracted from papers in the Atlas)

 t(6;12)(p21;q15) MDM2/RUNX2

External links

Mitelman database t(6;12)(p21;q15) [CaseList]    t(6;12)(p21;q15) [Transloc - MCList] MDM2/RUNX2 [Fusion - MCList]
COSMIC[ MDM2 ]   [ RUNX2 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(6;12)(p21;q15) MDM2/RUNX2
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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indexed on : Fri Feb 23 20:39:44 CET 2018

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