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t(6;12)(q22;p11) PPFIBP1/ROS1

Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 106903
Phylum Lung, Heart, Skin, Other: Skin::
WHO/OMS Classification Lung, Heart, Skin, Other
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Skin: Melanocytic neoplasm, special type

Genes involved and Proteins

Gene NamePPFIBP1
Location 12p11.23

Gene NameROS1
Location 6q22.1

Bibliography

Kinase fusions are frequent in Spitz tumours and spitzoid melanomas
Wiesner T, He J, Yelensky R, Esteve-Puig R, Botton T, Yeh I, Lipson D, Otto G, Brennan K, Murali R, Garrido M, Miller VA, Ross JS, Berger MF, Sparatta A, Palmedo G, Cerroni L, Busam KJ, Kutzner H, Cronin MT, Stephens PJ, Bastian BC
Nat Commun 2014;5:3116
PMID 24445538
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(6;12)(q22;p11) PPFIBP1/ROS1

External links

Mitelman database t(6;12)(q22;p11) [CaseList]     t(6;12)(q22;p11) [Transloc - MCList]   PPFIBP1/ROS1 Fusion - MCList]
COSMIC[ PPFIBP1 ]   [ ROS1 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(6;12)(q22;p11) PPFIBP1/ROS1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Wed Nov 28 16:43:22 CET 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.