Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

t(6;12)(q22;q24) ZCCHC8/ROS1

Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 106906
Phylum Nervous system: Central Nervous system::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Central Nervous system: Astrocytoma, grade III-IV/Glioblastoma

Genes involved and Proteins

Gene NameZCCHC8
Location 12q24.31

Gene NameROS1
Location 6q22.1

Bibliography

Identification of ZCCHC8 as fusion partner of ROS1 in a case of congenital glioblastoma multiforme with a t(6;12)(q21;q24
Coccé MC, Mardin BR, Bens S, Stütz AM, Lubieniecki F, Vater I, Korbel JO, Siebert R, Alonso CN, Gallego MS
3) Genes Chromosomes Cancer
PMID 27121553
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(6;12)(q22;q24) ZCCHC8/ROS1

External links

Mitelman database t(6;12)(q22;q24) [CaseList]     t(6;12)(q22;q24) [Transloc - MCList]   ZCCHC8/ROS1 Fusion - MCList]
COSMIC[ ZCCHC8 ]   [ ROS1 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(6;12)(q22;q24) ZCCHC8/ROS1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Oct 5 17:23:36 CEST 2018


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.