Atlas of Genetics and Cytogenetics in Oncology and Haematology

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t(6;15)(q24;q25) MEF2A::GRM1

(Note : for Links provided by Atlas : click)


Atlas_Id 106944
Phylum Bones: Bones::
WHO/OMS Classification Bones
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Bones: Chondromyxoid fibroma

Genes involved and Proteins

Gene NameMEF2A
Location 15q26.3

Gene NameGRM1
Location 6q24.3


GRM1 is upregulated through gene fusion and promoter swapping in chondromyxoid fibroma
Nord KH, Lilljebjörn H, Vezzi F, Nilsson J, Magnusson L, Tayebwa J, de Jong D, Bovée JV, Hogendoorn PC, Szuhai K
Nat Genet 2014 May;46(5):474-7
PMID 24658000

Translocations implicated (Data extracted from papers in the Atlas)

 t(6;15)(q24;q25) MEF2A/GRM1

External links

Mitelman database t(6;15)(q24;q25) [CaseList]     t(6;15)(q24;q25) [Transloc - MCList]   MEF2A/GRM1 Fusion - MCList]
COSMIC[ MEF2A ]   [ GRM1 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(6;15)(q24;q25) MEF2A::GRM1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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indexed on : Tue Oct 12 14:52:51 CEST 2021

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