| Identity |
| Atlas_Id | 107591 |
| Phylum | Lung, Heart, Skin, Other: Skin:: |
| WHO/OMS Classification | Lung, Heart, Skin, Other |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Skin: Malignant melanoma |
| Genes involved and Proteins |
| Gene Name | TAX1BP1 |
| Location | 7p15.2 |
| Gene Name | BRAF |
| Location | 7q34 |
| Bibliography |
| BRAF fusions define a distinct molecular subset of melanomas with potential sensitivity to MEK inhibition |
| Hutchinson KE, Lipson D, Stephens PJ, Otto G, Lehmann BD, Lyle PL, Vnencak-Jones CL, Ross JS, Pietenpol JA, Sosman JA, Puzanov I, Miller VA, Pao W |
| Clin Cancer Res 2013 Dec 15;19(24):6696-702 |
| PMID 24345920 |
| The landscape of kinase fusions in cancer |
| Stransky N, Cerami E, Schalm S, Kim JL, Lengauer C |
| Nat Commun 2014 Sep 10;5:4846 |
| PMID 25204415 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| t(7;7)(p15;q34) TAX1BP1/BRAF | |
| External links |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Dec 14 18:43:22 CET 2020 |
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