Written | 08-2018 | Jean-Loup Huret, Philippe Dessen |
Identity |
Atlas_Id | 107591 |
Phylum | Lung, Heart, Skin, Other: Skin:: |
WHO/OMS Classification | Lung, Heart, Skin, Other |
Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
Clinics and Pathology |
Disease | Skin: Malignant melanoma |
Genes involved and Proteins |
Gene Name | TAX1BP1 |
Location | 7p15.2 |
Gene Name | BRAF |
Location | 7q34 |
Bibliography |
BRAF fusions define a distinct molecular subset of melanomas with potential sensitivity to MEK inhibition |
Hutchinson KE, Lipson D, Stephens PJ, Otto G, Lehmann BD, Lyle PL, Vnencak-Jones CL, Ross JS, Pietenpol JA, Sosman JA, Puzanov I, Miller VA, Pao W |
Clin Cancer Res 2013 Dec 15;19(24):6696-702 |
PMID 24345920 |
The landscape of kinase fusions in cancer |
Stransky N, Cerami E, Schalm S, Kim JL, Lengauer C |
Nat Commun 2014 Sep 10;5:4846 |
PMID 25204415 |
Translocations implicated (Data extracted from papers in the Atlas) |
t(7;7)(p15;q34) TAX1BP1/BRAF | |
External links |
REVIEW articles | automatic search in PubMed |
Last year articles | automatic search in PubMed |
© Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Thu Feb 14 17:57:36 CET 2019 |
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