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t(7;7)(p21;q34) TMEM106B/BRAF

Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 107599
Phylum Nervous system: Central Nervous system::
WHO/OMS Classification Nervous system
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Central Nervous system: Astrocytoma, grade I-II

Genes involved and Proteins

Gene NameTMEM106B
Location 7p21.3

Gene NameBRAF
Location 7q34

Bibliography

A novel, potentially targetable TMEM106B-BRAF fusion in pleomorphic xanthoastrocytoma
Hsiao SJ, Karajannis MA, Diolaiti D, Mansukhani MM, Bender JG, Kung AL, Garvin JH Jr
Cold Spring Harb Mol Case Stud 2017 Mar;3(2):a001396
PMID 28299358
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(7;7)(p21;q34) TMEM106B/BRAF

External links

Mitelman database t(7;7)(p21;q34) [CaseList]     t(7;7)(p21;q34) [Transloc - MCList]   TMEM106B/BRAF Fusion - MCList]
COSMIC[ TMEM106B ]   [ BRAF ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(7;7)(p21;q34) TMEM106B/BRAF
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Wed Nov 28 16:44:20 CET 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.