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t(7;7)(q34;q36) AGAP3/BRAF

Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 107730
Phylum Digestive organs: Colon-Rectum::
WHO/OMS Classification Digestive organs
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Colon-Rectum: Adenocarcinoma

Genes involved and Proteins

Gene NameAGAP3
Location 7q36.1

Gene NameBRAF
Location 7q34

Bibliography

The distribution of BRAF gene fusions in solid tumors and response to targeted therapy
Ross JS, Wang K, Chmielecki J, Gay L, Johnson A, Chudnovsky J, Yelensky R, Lipson D, Ali SM, Elvin JA, Vergilio JA, Roels S, Miller VA, Nakamura BN, Gray A, Wong MK, Stephens PJ
Int J Cancer 2016 Feb 15;138(4):881-90
PMID 26314551
 
A Systematic Analysis of Oncogenic Gene Fusions in Primary Colon Cancer
Kloosterman WP, Coebergh van den Braak RRJ, Pieterse M, van Roosmalen MJ, Sieuwerts AM, Stangl C, Brunekreef R, Lalmahomed ZS, Ooft S, van Galen A, Smid M, Lefebvre A, Zwartkruis F, Martens JWM, Foekens JA, Biermann K, Koudijs MJ, Ijzermans JNM, Voest EE
Cancer Res 2017 Jul 15;77(14):3814-3822
PMID 28512242
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(7;7)(q34;q36) AGAP3/BRAF

External links

Mitelman database t(7;7)(q34;q36) [CaseList]     t(7;7)(q34;q36) [Transloc - MCList]   AGAP3/BRAF Fusion - MCList]
COSMIC[ AGAP3 ]   [ BRAF ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(7;7)(q34;q36) AGAP3/BRAF
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Wed Nov 28 16:44:56 CET 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.