Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

t(7;10)(q34;q11) TRIM24::RET

(Note : for Links provided by Atlas : click)


Atlas_Id 107369
Phylum Neuro-Endocrine/Endocrine system: Thyroid::
WHO/OMS Classification Neuro-Endocrine/Endocrine system
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Thyroid: Adenocarcinoma

Genes involved and Proteins

Gene NameTRIM24
Location 7q33

Gene NameRET
Location 10q11.21


The transcription coactivator HTIF1 and a related protein are fused to the RET receptor tyrosine kinase in childhood papillary thyroid carcinomas
Klugbauer S, Rabes HM
Oncogene 1999 Jul 29;18(30):4388-93
PMID 10439047
Pattern of radiation-induced RET and NTRK1 rearrangements in 191 post-chernobyl papillary thyroid carcinomas: biological, phenotypic, and clinical implications
Rabes HM, Demidchik EP, Sidorow JD, Lengfelder E, Beimfohr C, Hoelzel D, Klugbauer S
Clin Cancer Res 2000 Mar;6(3):1093-103
PMID 10741739

Translocations implicated (Data extracted from papers in the Atlas)

 t(7;10)(q34;q11) TRIM24/RET

External links

Mitelman database t(7;10)(q34;q11) [CaseList]     t(7;10)(q34;q11) [Transloc - MCList]   TRIM24/RET Fusion - MCList]
COSMIC[ TRIM24 ]   [ RET ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(7;10)(q34;q11) TRIM24::RET
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Oct 12 14:54:03 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us