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t(7;15)(p21;q21) HMGN2P46/ETV1

Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 107432
Phylum Male organs: Prostate::
WHO/OMS Classification Male organs
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Prostate: Adenocarcinoma

Genes involved and Proteins

Gene NameHMGN2P46
Location 15q21.1

Gene NameETV1
Location 7p21.2

Bibliography

Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer
Tomlins SA, Laxman B, Dhanasekaran SM, Helgeson BE, Cao X, Morris DS, Menon A, Jing X, Cao Q, Han B, Yu J, Wang L, Montie JE, Rubin MA, Pienta KJ, Roulston D, Shah RB, Varambally S, Mehra R, Chinnaiyan AM
Nature 2007 Aug 2;448(7153):595-9
PMID 17671502
 
Heterogeneity and clinical significance of ETV1 translocations in human prostate cancer
Attard G, Clark J, Ambroisine L, Mills IG, Fisher G, Flohr P, Reid A, Edwards S, Kovacs G, Berney D, Foster C, Massie CE, Fletcher A, De Bono JS, Scardino P, Cuzick J, Cooper CS; Transatlantic Prostate Group
Br J Cancer 2008 Jul 22;99(2):314-20
PMID 18594527
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(7;15)(p21;q21) HMGN2P46/ETV1

External links

Mitelman database t(7;15)(p21;q21) [CaseList]     t(7;15)(p21;q21) [Transloc - MCList]   HMGN2P46/ETV1 Fusion - MCList]
COSMIC[ HMGN2P46 ]   [ ETV1 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(7;15)(p21;q21) HMGN2P46/ETV1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Wed Nov 28 16:45:38 CET 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.