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t(7;17)(p15;q11) JAZF1/SUZ12

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)


Atlas_Id 113363
Phylum Female organs: Uterus::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

Clinics and Pathology

Disease Female organs: Uterus:Endometrial stromal sarcoma

Genes involved and Proteins

Gene NameJAZF1
Location 7p15.2-p15.1

Gene NameSUZ12
Location 17q11.2


Frequent fusion of the JAZF1 and JJAZ1 genes in endometrial stromal tumors
Koontz JI, Soreng AL, Nucci M, Kuo FC, Pauwels P, van Den Berghe H, Dal Cin P, Fletcher JA, Sklar J
Proc Natl Acad Sci U S A 2001 May 22;98(11):6348-53
PMID 11371647
Cytogenetic and molecular genetic analyses of endometrial stromal sarcoma: nonrandom involvement of chromosome arms 6p and 7p and confirmation of JAZF1/JJAZ1 gene fusion in t(7;17)
Micci F, Walter CU, Teixeira MR, Panagopoulos I, Bjerkehagen B, Saeter G, Heim S
Cancer Genet Cytogenet 2003 Jul 15;144(2):119-24
PMID 12850374
Molecular analysis of the JAZF1-JJAZ1 gene fusion by RT-PCR and fluorescence in situ hybridization in endometrial stromal neoplasms
Nucci MR, Harburger D, Koontz J, Dal Cin P, Sklar J
Am J Surg Pathol 2007 Jan;31(1):65-70
PMID 17197920

Translocations implicated (Data extracted from papers in the Atlas)

 t(7;17)(p15;q11) JAZF1/SUZ12

External links

Mitelman database t(7;17)(p15;q11) [CaseList]    t(7;17)(p15;q11) [Transloc - MCList] JAZF1/SUZ12 [Fusion - MCList]
COSMIC[ JAZF1 ]   [ SUZ12 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(7;17)(p15;q11) JAZF1/SUZ12
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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indexed on : Fri Feb 23 20:41:28 CET 2018

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