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t(7;17)(q34;q21) CDC27/BRAF

Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 107468
Phylum Lung, Heart, Skin, Other: Skin::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Skin: Malignant melanoma

Genes involved and Proteins

Gene NameCDC27
Location 17q21.32

Gene NameBRAF
Location 7q34

Bibliography

BRAF fusions define a distinct molecular subset of melanomas with potential sensitivity to MEK inhibition
Hutchinson KE, Lipson D, Stephens PJ, Otto G, Lehmann BD, Lyle PL, Vnencak-Jones CL, Ross JS, Pietenpol JA, Sosman JA, Puzanov I, Miller VA, Pao W
Clin Cancer Res 2013 Dec 15;19(24):6696-702
PMID 24345920
 
The landscape of kinase fusions in cancer
Stransky N, Cerami E, Schalm S, Kim JL, Lengauer C
Nat Commun 2014 Sep 10;5:4846
PMID 25204415
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(7;17)(q34;q21) CDC27/BRAF

External links

Mitelman database t(7;17)(q34;q21) [CaseList]     t(7;17)(q34;q21) [Transloc - MCList]   CDC27/BRAF Fusion - MCList]
COSMIC[ CDC27 ]   [ BRAF ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(7;17)(q34;q21) CDC27/BRAF
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Fri Oct 5 17:25:51 CEST 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.