t(8;8)(q13;q24) PVT1/EYA1

Identity

Atlas_Id	108120
Phylum	Lung, Heart, Skin, Other: Lung::
WHO/OMS Classification	Lung, Heart, Skin, Other
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease

Lung: Undifferentiated carcinoma, small cell

Genes involved and Proteins

Gene Name	PVT1
Location	8q24.21

Gene Name	EYA1
Location	8q13.3

Bibliography

Genomic organization and evolution of double minutes/homogeneously staining regions with MYC amplification in human cancer

L'Abbate A, Macchia G, D'Addabbo P, Lonoce A, Tolomeo D, Trombetta D, Kok K, Bartenhagen C, Whelan CW, Palumbo O, Severgnini M, Cifola I, Dugas M, Carella M, De Bellis G, Rocchi M, Carbone L, Storlazzi CT

Nucleic Acids Res 2014 Aug;42(14):9131-45

PMID 25034695

Translocations implicated (Data extracted from papers in the Atlas)

	t(8;8)(q13;q24) PVT1/EYA1

External links

Mitelman database	t(8;8)(q13;q24) [CaseList]     t(8;8)(q13;q24) [Transloc - MCList]   PVT1/EYA1 Fusion - MCList]
COSMIC	[ PVT1 ]   [ EYA1 ]
arrayMap	arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease database	t(8;8)(q13;q24) PVT1/EYA1

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Wed Nov 28 16:46:39 CET 2018

For comments and suggestions or contributions, please contact us