Written | 08-2018 | Jean-Loup Huret, Philippe Dessen |
Identity |
Atlas_Id | 108120 |
Phylum | Lung, Heart, Skin, Other: Lung:: |
WHO/OMS Classification | Lung, Heart, Skin, Other |
Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
Clinics and Pathology |
Disease | Lung: Undifferentiated carcinoma, small cell |
Genes involved and Proteins |
Gene Name | PVT1 |
Location | 8q24.21 |
Gene Name | EYA1 |
Location | 8q13.3 |
Bibliography |
Genomic organization and evolution of double minutes/homogeneously staining regions with MYC amplification in human cancer |
L'Abbate A, Macchia G, D'Addabbo P, Lonoce A, Tolomeo D, Trombetta D, Kok K, Bartenhagen C, Whelan CW, Palumbo O, Severgnini M, Cifola I, Dugas M, Carella M, De Bellis G, Rocchi M, Carbone L, Storlazzi CT |
Nucleic Acids Res 2014 Aug;42(14):9131-45 |
PMID 25034695 |
Translocations implicated (Data extracted from papers in the Atlas) |
t(8;8)(q13;q24) PVT1/EYA1 | |
External links |
REVIEW articles | automatic search in PubMed |
Last year articles | automatic search in PubMed |
© Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Thu Feb 14 17:59:32 CET 2019 |
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