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t(8;8)(q22;q22) PLEKHF2/NDUFAF6

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 103245
Phylum Female organs: Breast::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Female organs: Breast:Adenocarcinoma

Genes involved and Proteins

Gene NamePLEKHF2
Location 8q22.1

Gene NameNDUFAF6
Location 8q22.1

Bibliography

BreakTrans: uncovering the genomic architecture of gene fusions
Chen K, Navin NE, Wang Y, Schmidt HK, Wallis JW, Niu B, Fan X, Zhao H, McLellan MD, Hoadley KA, Mardis ER, Ley TJ, Perou CM, Wilson RK, Ding L
Genome Biol 2013 Aug 23;14(8):R87
PMID 23972288
 
The landscape and therapeutic relevance of cancer-associated transcript fusions
Yoshihara K, Wang Q, Torres-Garcia W, Zheng S, Vegesna R, Kim H, Verhaak RG
Oncogene 2015 Sep 10;34(37):4845-54
PMID 25500544
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(8;8)(q22;q22) PLEKHF2/NDUFAF6

External links

Mitelman database t(8;8)(q22;q22) [CaseList]     t(8;8)(q22;q22) [Transloc - MCList]   PLEKHF2/NDUFAF6 Fusion - MCList]
COSMIC[ PLEKHF2 ]   [ NDUFAF6 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(8;8)(q22;q22) PLEKHF2/NDUFAF6
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Fri Jun 22 18:03:19 CEST 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.