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t(8;8)(q24;q24) PVT1/MYC

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)


Atlas_Id 108264
Phylum Female organs: Breast::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

Clinics and Pathology

Disease Female organs: Breast:Adenocarcinoma

Genes involved and Proteins

Gene NamePVT1
Location 8q24.21

Gene NameMYC
Location 14q23.3


Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer
Robinson DR, Kalyana-Sundaram S, Wu YM, Shankar S, Cao X, Ateeq B, Asangani IA, Iyer M, Maher CA, Grasso CS, Lonigro RJ, Quist M, Siddiqui J, Mehra R, Jing X, Giordano TJ, Sabel MS, Kleer CG, Palanisamy N, Natrajan R, Lambros MB, Reis-Filho JS, Kumar-Sinha C, Chinnaiyan AM
Nat Med 2011 Nov 20;17(12):1646-51
PMID 22101766
Gene fusions associated with recurrent amplicons represent a class of passenger aberrations in breast cancer
Kalyana-Sundaram S, Shankar S, Deroo S, Iyer MK, Palanisamy N, Chinnaiyan AM, Kumar-Sinha C
Neoplasia 2012 Aug;14(8):702-8
PMID 22952423

Translocations implicated (Data extracted from papers in the Atlas)

 t(8;8)(q24;q24) PVT1/MYC

External links

Mitelman database t(8;8)(q24;q24) [CaseList]    t(8;8)(q24;q24) [Transloc - MCList] PVT1/MYC [Fusion - MCList]
COSMIC[ PVT1 ]   [ MYC ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(8;8)(q24;q24) PVT1/MYC
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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indexed on : Fri Feb 23 20:42:31 CET 2018

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