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t(8;9)(q13;p22) MYBL1/NFIB

Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 108253
Phylum Head and Neck: Salivary gland::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Salivary gland: Adenoid cystic carcinoma

Genes involved and Proteins

Gene NameMYBL1
Location 8q13.1

Gene NameNFIB
Location 9p23

Bibliography

Recurrent Fusions in MYB and MYBL1 Define a Common, Transcription Factor-Driven Oncogenic Pathway in Salivary Gland Adenoid Cystic Carcinoma
Brayer KJ, Frerich CA, Kang H, Ness SA
Cancer Discov 2016 Feb;6(2):176-87
PMID 26631070
 
Novel MYBL1 Gene Rearrangements with Recurrent MYBL1-NFIB Fusions in Salivary Adenoid Cystic Carcinomas Lacking t(6;9) Translocations
Mitani Y, Liu B, Rao PH, Borra VJ, Zafereo M, Weber RS, Kies M, Lozano G, Futreal PA, Caulin C, El-Naggar AK
Clin Cancer Res 2016 Feb 1;22(3):725-33
PMID 26631609
 
Whole-Genome Sequencing of Salivary Gland Adenoid Cystic Carcinoma
Rettig EM, Talbot CC Jr, Sausen M, Jones S, Bishop JA, Wood LD, Tokheim C, Niknafs N, Karchin R, Fertig EJ, Wheelan SJ, Marchionni L, Considine M, Fakhry C, Papadopoulos N, Kinzler KW, Vogelstein B, Ha PK, Agrawal N
Cancer Prev Res (Phila) 2016 Apr;9(4):265-74
PMID 26862087
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(8;9)(q13;p22) MYBL1/NFIB

External links

Mitelman database t(8;9)(q13;p22) [CaseList]     t(8;9)(q13;p22) [Transloc - MCList]   MYBL1/NFIB Fusion - MCList]
COSMIC[ MYBL1 ]   [ NFIB ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(8;9)(q13;p22) MYBL1/NFIB
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Fri Oct 5 17:27:16 CEST 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.