t(8;11)(p12;q14) TENM4/NRG1

0000-00-00   Jean-Loup Huret , Philippe Dessen 

(Note: the fusion was discovered by NGS. Many chromosome rearrangement mechanisms such as translocation, inversion,deletion or complex rearrangement may lead to the same fusion)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute

Summary

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Genes Involved and Proteins

Gene name

TENM4

Location

11q14.1

Gene name

NRG1

Location

8p12

Highly cited references

Pubmed IDYearTitleCitations
334135572021NRG1 fusions in breast cancer.3

Bibliography

Pubmed IDLast YearTitleAuthors
105238511999gamma-heregulin is the product of a chromosomal translocation fusing the DOC4 and HGL/NRG1 genes in the MDA-MB-175 breast cancer cell line.Wang XZ et al
105973121999Gamma-heregulin: a fusion gene of DOC-4 and neuregulin-1 derived from a chromosome translocation.Liu X et al
216229592011A novel bioinformatics pipeline for identification and characterization of fusion transcripts in breast cancer and normal cell lines.Asmann YW et al

Citation

Jean-Loup Huret ; Philippe Dessen

t(8;11)(p12;q14) TENM4/NRG1

Atlas Genet Cytogenet Oncol Haematol. 0000-00-00

Online version: http://atlasgeneticsoncology.org/solid-tumor/107817/t(8;11)(p12;q14)-tenm4-nrg1