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t(8;12)(p21;p13) PEX5/LPL

Written2018-01Jean-Loup Huret, Philippe Dessen

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Atlas_Id 113329
Phylum Female organs: Uterus::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

Clinics and Pathology

Disease Female organs: Uterus:Squamous cell carcinoma

Genes involved and Proteins

Gene NamePEX5
Location 12p13.31

Gene NameLPL
Location 1p36.12


Lipoprotein lipase is frequently overexpressed or translocated in cervical squamous cell carcinoma and promotes invasiveness through the non-catalytic C terminus
Carter SA, Foster NA, Scarpini CG, Chattopadhyay A, Pett MR, Roberts I, Coleman N
Br J Cancer 2012 Aug 7;107(4):739-47
PMID 22782350

Translocations implicated (Data extracted from papers in the Atlas)

 t(8;12)(p21;p13) PEX5/LPL

External links

Mitelman database t(8;12)(p21;p13) [CaseList]    t(8;12)(p21;p13) [Transloc - MCList] PEX5/LPL [Fusion - MCList]
COSMIC[ PEX5 ]   [ LPL ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(8;12)(p21;p13) PEX5/LPL
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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indexed on : Fri Feb 23 20:42:53 CET 2018

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