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t(8;22)(p21;q12) PPP2R2A/CHEK2

Written2018-01Jean-Loup Huret, Philippe Dessen

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Atlas_Id 109453
Phylum Lung, Heart, Skin, Other: Mediastinum::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

Clinics and Pathology

Disease Lung, Heart, Skin, Other: Mediastinum:Teratoma (mature and immature)

Genes involved and Proteins

Gene NamePPP2R2A
Location 8p21.2

Gene NameCHEK2


Fusion of the tumor-suppressor gene CHEK2 and the gene for the regulatory subunit B of protein phosphatase 2 PPP2R2A in childhood teratoma
Jin Y, Mertens F, Kullendorff CM, Panagopoulos I
Neoplasia 2006 May;8(5):413-8
PMID 16790090

Translocations implicated (Data extracted from papers in the Atlas)

 t(8;22)(p21;q12) PPP2R2A/CHEK2

External links

Mitelman database t(8;22)(p21;q12) [CaseList]    t(8;22)(p21;q12) [Transloc - MCList] PPP2R2A/CHEK2 [Fusion - MCList]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(8;22)(p21;q12) PPP2R2A/CHEK2
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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indexed on : Fri Feb 23 20:43:25 CET 2018

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