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t(9;12)(q33;q21) NR6A1/TRHDE

Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 108302
Phylum Soft Tissues: Soft Tissues::
WHO/OMS Classification Soft Tissues
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Soft Tissues: Liposarcoma, dedifferentiated

Genes involved and Proteins

Gene NameNR6A1
Location 9q33.3

Gene NameTRHDE
Location 12q21.1

Bibliography

Frequent alterations and epigenetic silencing of differentiation pathway genes in structurally rearranged liposarcomas
Taylor BS, DeCarolis PL, Angeles CV, Brenet F, Schultz N, Antonescu CR, Scandura JM, Sander C, Viale AJ, Socci ND, Singer S
Cancer Discov 2011 Dec;1(7):587-97
PMID 22328974
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(9;12)(q33;q21) NR6A1/TRHDE

External links

Mitelman database t(9;12)(q33;q21) [CaseList]     t(9;12)(q33;q21) [Transloc - MCList]   NR6A1/TRHDE Fusion - MCList]
COSMIC[ NR6A1 ]   [ TRHDE ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(9;12)(q33;q21) NR6A1/TRHDE
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Wed Nov 28 16:49:32 CET 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.