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t(X;1)(p11;p34) TFE3/SFPQ

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)


Atlas_Id 109649
Phylum Urinary system: Kidney::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

Clinics and Pathology

Disease Urinary system: Kidney:Adenocarcinoma

Genes involved and Proteins

Gene NameTFE3
Location Xp11.23

Gene NameSFPQ
Location 1p34.3


Secondary PSF/TFE3-associated renal cell carcinoma in a child treated for genitourinary rhabdomyosarcoma
Brassesco MS, Valera ET, Bonilha TA, Scrideli CA, Carvalho de Oliveira J, Pezuk JA, Barros Silva GE, Costa RS, Tone LG
Cancer Genet 2011 Feb;204(2):108-10
PMID 21504709
Comprehensive molecular characterization of clear cell renal cell carcinoma
Cancer Genome Atlas Research Network
Nature 2013 Jul 4;499(7456):43-9
PMID 23792563
The landscape and therapeutic relevance of cancer-associated transcript fusions
Yoshihara K, Wang Q, Torres-Garcia W, Zheng S, Vegesna R, Kim H, Verhaak RG
Oncogene 2015 Sep 10;34(37):4845-54
PMID 25500544
Fusion of splicing factor genes PSF and NonO (p54nrb) to the TFE3 gene in papillary renal cell carcinoma
Clark J, Lu YJ, Sidhar SK, Parker C, Gill S, Smedley D, Hamoudi R, Linehan WM, Shipley J, Cooper CS
Oncogene 1997 Oct;15(18):2233-9
PMID 9393982

Translocations implicated (Data extracted from papers in the Atlas)

 t(X;1)(p11;p34) TFE3/SFPQ

External links

Mitelman database t(X;1)(p11;p34) [CaseList]    t(X;1)(p11;p34) [Transloc - MCList] TFE3/SFPQ [Fusion - MCList]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(X;1)(p11;p34) TFE3/SFPQ
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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indexed on : Fri Feb 23 20:44:36 CET 2018

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