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t(X;19)(q13;q13) CIC/FOXO4

Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 108657
Phylum Soft Tissues: Soft Tissues::
WHO/OMS Classification Soft Tissues
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Soft Tissues: Undifferentiated round cell sarcoma

Genes involved and Proteins

Gene NameCIC
Location 19q13.2

Gene NameFOXO4
Location Xq13.1

Bibliography

A novel CIC-FOXO4 gene fusion in undifferentiated small round cell sarcoma: a genetically distinct variant of Ewing-like sarcoma
Sugita S, Arai Y, Tonooka A, Hama N, Totoki Y, Fujii T, Aoyama T, Asanuma H, Tsukahara T, Kaya M, Shibata T, Hasegawa T
Am J Surg Pathol 2014 Nov;38(11):1571-6
PMID 25007147
 
The genomic landscape of the Ewing Sarcoma family of tumors reveals recurrent STAG2 mutation
Brohl AS, Solomon DA, Chang W, Wang J, Song Y, Sindiri S, Patidar R, Hurd L, Chen L, Shern JF, Liao H, Wen X, Gerard J, Kim JS, Lopez Guerrero JA, Machado I, Wai DH, Picci P, Triche T, Horvai AE, Miettinen M, Wei JS, Catchpool D, Llombart-Bosch A, Waldman T, Khan J
PLoS Genet 2014 Jul 10;10(7):e1004475
PMID 25010205
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(X;19)(q13;q13) CIC/FOXO4

External links

Mitelman database t(X;19)(q13;q13) [CaseList]     t(X;19)(q13;q13) [Transloc - MCList]   CIC/FOXO4 Fusion - MCList]
COSMIC[ CIC ]   [ FOXO4 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(X;19)(q13;q13) CIC/FOXO4
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Wed Nov 28 16:50:45 CET 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.