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t(10;10)(q24;q26) FGFR2/MGEA5

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 104633
Phylum Digestive organs: Gallbladder::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Digestive organs: Gallbladder:Adenocarcinoma

Genes involved and Proteins

Gene NameFGFR2
Location 10q26.13

Gene NameMGEA5
Location 10q24.32

Bibliography

Integrated genomic characterization reveals novel, therapeutically relevant drug targets in FGFR and EGFR pathways in sporadic intrahepatic cholangiocarcinoma
Borad MJ, Champion MD, Egan JB, Liang WS, Fonseca R, Bryce AH, McCullough AE, Barrett MT, Hunt K, Patel MD, Young SW, Collins JM, Silva AC, Condjella RM, Block M, McWilliams RR, Lazaridis KN, Klee EW, Bible KC, Harris P, Oliver GR, Bhavsar JD, Nair AA, Middha S, Asmann Y, Kocher JP, Schahl K, Kipp BR, Barr Fritcher EG, Baker A, Aldrich J, Kurdoglu A, Izatt T, Christoforides A, Cherni I, Nasser S, Reiman R, Phillips L, McDonald J, Adkins J, Mastrian SD, Placek P, Watanabe AT, Lobello J, Han H, Von Hoff D, Craig DW, Stewart AK, Carpten JD
PLoS Genet 2014 Feb 13;10(2):e1004135
PMID 24550739
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(10;10)(q24;q26) FGFR2/MGEA5

External links

Mitelman database t(10;10)(q24;q26) [CaseList]     t(10;10)(q24;q26) [Transloc - MCList]   FGFR2/MGEA5 Fusion - MCList]
COSMIC[ FGFR2 ]   [ MGEA5 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(10;10)(q24;q26) FGFR2/MGEA5
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Fri Jun 22 18:07:17 CEST 2018


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