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t(10;12)(q26;q12) FGFR2/PPHLN1

Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 100344
Phylum Digestive organs: Gallbladder::
WHO/OMS Classification Digestive organs
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Gallbladder: Adenocarcinoma

Genes involved and Proteins

Gene NameFGFR2
Location 10q26.13

Gene NamePPHLN1
Location 12q12

Bibliography

Massive parallel sequencing uncovers actionable FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma
Sia D, Losic B, Moeini A, Cabellos L, Hao K, Revill K, Bonal D, Miltiadous O, Zhang Z, Hoshida Y, Cornella H, Castillo-Martin M, Pinyol R, Kasai Y, Roayaie S, Thung SN, Fuster J, Schwartz ME, Waxman S, Cordon-Cardo C, Schadt E, Mazzaferro V, Llovet JM
Nat Commun 2015 Jan 22;6:6087
PMID 25608663
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(10;12)(q26;q12) FGFR2/PPHLN1

External links

Mitelman database t(10;12)(q26;q12) [CaseList]     t(10;12)(q26;q12) [Transloc - MCList]   FGFR2/PPHLN1 Fusion - MCList]
COSMIC[ FGFR2 ]   [ PPHLN1 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(10;12)(q26;q12) FGFR2/PPHLN1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Wed Nov 28 16:52:10 CET 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.