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t(10;14)(q11;q22) KTN1/RET

Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 100359
Phylum Neuro-Endocrine/Endocrine system: Thyroid::
WHO/OMS Classification Neuro-Endocrine/Endocrine system
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Thyroid: Adenocarcinoma

Genes involved and Proteins

Gene NameKTN1
Location 14q22.3

Gene NameRET
Location 10q11.21

Bibliography

Pattern of radiation-induced RET and NTRK1 rearrangements in 191 post-chernobyl papillary thyroid carcinomas: biological, phenotypic, and clinical implications
Rabes HM, Demidchik EP, Sidorow JD, Lengfelder E, Beimfohr C, Hoelzel D, Klugbauer S
Clin Cancer Res 2000 Mar;6(3):1093-103
PMID 10741739
 
Translocation t(10;14)(q11
Salassidis K, Bruch J, Zitzelsberger H, Lengfelder E, Kellerer AM, Bauchinger M
2:q22 1) fusing the kinetin to the RET gene creates a novel rearranged form (PTC8) of the RET proto-oncogene in radiation-induced childhood papillary thyroid carcinoma
PMID 10850414
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(10;14)(q11;q22) KTN1/RET

External links

Mitelman database t(10;14)(q11;q22) [CaseList]     t(10;14)(q11;q22) [Transloc - MCList]   KTN1/RET Fusion - MCList]
COSMIC[ KTN1 ]   [ RET ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(10;14)(q11;q22) KTN1/RET
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Wed Nov 28 16:52:14 CET 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.