Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

t(10;17)(q22;p13) YWHAE/NUTM2B

Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 100397
Phylum Urinary system: Kidney::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Kidney: Clear cell sarcoma

Genes involved and Proteins

Gene NameYWHAE
Location 17p13.3

Gene NameNUTM2B
Location 10q22.3

Bibliography

Characterization of the chromosomal translocation t(10;17)(q22;p13) in clear cell sarcoma of kidney
O'Meara E, Stack D, Lee CH, Garvin AJ, Morris T, Argani P, Han JS, Karlsson J, Gisselson D, Leuschner I, Gessler M, Graf N, Fletcher JA, O'Sullivan MJ
J Pathol 2012 May;227(1):72-80
PMID 22294382
 
Activation of human telomerase reverse transcriptase through gene fusion in clear cell sarcoma of the kidney
Karlsson J, Lilljebjörn H, Holmquist Mengelbier L, Valind A, Rissler M, Øra I, Fioretos T, Gisselsson D
Cancer Lett 2015 Feb 28;357(2):498-501
PMID 25481751
 
The clinical phenotype of YWHAE-NUTM2B/E positive pediatric clear cell sarcoma of the kidney
Gooskens SL, Kenny C, Lazaro A, O'Meara E, van Tinteren H, Spreafico F, Vujanic G, Leuschner I, Coulomb-L'Herminé A, Perotti D, de Camargo B, Bergeron C, Acha García T, Tanaka M, Pieters R, Pritchard-Jones K, Graf N, van den Heuvel-Eibrink MM, O'Sullivan MJ
Genes Chromosomes Cancer 2016 Feb;55(2):143-7
PMID 26542179
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(10;17)(q22;p13) YWHAE/NUTM2B

External links

Mitelman database t(10;17)(q22;p13) [CaseList]     t(10;17)(q22;p13) [Transloc - MCList]   YWHAE/NUTM2B Fusion - MCList]
COSMIC[ YWHAE ]   [ NUTM2B ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(10;17)(q22;p13) YWHAE/NUTM2B
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Oct 5 17:32:08 CEST 2018


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.