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t(10;17)(q22;p13) YWHAE/NUTM2B

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)


Atlas_Id 109675
Phylum Urinary system: Kidney::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

Clinics and Pathology

Disease Urinary system: Kidney:Clear cell sarcoma

Genes involved and Proteins

Gene NameYWHAE
Location 17p13.3

Gene NameNUTM2B


Characterization of the chromosomal translocation t(10;17)(q22;p13) in clear cell sarcoma of kidney
O'Meara E, Stack D, Lee CH, Garvin AJ, Morris T, Argani P, Han JS, Karlsson J, Gisselson D, Leuschner I, Gessler M, Graf N, Fletcher JA, O'Sullivan MJ
J Pathol 2012 May;227(1):72-80
PMID 22294382
Activation of human telomerase reverse transcriptase through gene fusion in clear cell sarcoma of the kidney
Karlsson J, Lilljebjörn H, Holmquist Mengelbier L, Valind A, Rissler M, Øra I, Fioretos T, Gisselsson D
Cancer Lett 2015 Feb 28;357(2):498-501
PMID 25481751
The clinical phenotype of YWHAE-NUTM2B/E positive pediatric clear cell sarcoma of the kidney
Gooskens SL, Kenny C, Lazaro A, O'Meara E, van Tinteren H, Spreafico F, Vujanic G, Leuschner I, Coulomb-L'Herminé A, Perotti D, de Camargo B, Bergeron C, Acha García T, Tanaka M, Pieters R, Pritchard-Jones K, Graf N, van den Heuvel-Eibrink MM, O'Sullivan MJ
Genes Chromosomes Cancer 2016 Feb;55(2):143-7
PMID 26542179

Translocations implicated (Data extracted from papers in the Atlas)

 t(10;17)(q22;p13) YWHAE/NUTM2B

External links

Mitelman database t(10;17)(q22;p13) [CaseList]    t(10;17)(q22;p13) [Transloc - MCList] YWHAE/NUTM2B [Fusion - MCList]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(10;17)(q22;p13) YWHAE/NUTM2B
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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indexed on : Fri Feb 23 20:46:26 CET 2018

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