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t(10;17)(q22;p13) YWHAE/NUTM2B

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 113403
Phylum Female organs: Uterus::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

Clinics and Pathology

Disease Female organs: Uterus:Endometrial stromal sarcoma

Genes involved and Proteins

Gene NameYWHAE
Location 17p13.3

Gene NameNUTM2B

Bibliography

14-3-3 fusion oncogenes in high-grade endometrial stromal sarcoma
Lee CH, Ou WB, Mariño-Enriquez A, Zhu M, Mayeda M, Wang Y, Guo X, Brunner AL, Amant F, French CA, West RB, McAlpine JN, Gilks CB, Yaffe MB, Prentice LM, McPherson A, Jones SJ, Marra MA, Shah SP, van de Rijn M, Huntsman DG, Dal Cin P, Debiec-Rychter M, Nucci MR, Fletcher JA
Proc Natl Acad Sci U S A 2012 Jan 17;109(3):929-34
PMID 22223660
 
The clinicopathologic features of YWHAE-FAM22 endometrial stromal sarcomas: a histologically high-grade and clinically aggressive tumor
Lee CH, Mariño-Enriquez A, Ou W, Zhu M, Ali RH, Chiang S, Amant F, Gilks CB, van de Rijn M, Oliva E, Debiec-Rychter M, Dal Cin P, Fletcher JA, Nucci MR
Am J Surg Pathol 2012 May;36(5):641-53
PMID 22456610
 
YWHAE rearrangement identified by FISH and RT-PCR in endometrial stromal sarcomas: genetic and pathological correlations
Croce S, Hostein I, Ribeiro A, Garbay D, Velasco V, Stoeckle E, Guyon F, Floquet A, Neuville A, Coindre JM, MacGrogan G, Chibon F
Mod Pathol 2013 Oct;26(10):1390-400
PMID 23599159
 
A prognosis based classification of undifferentiated uterine sarcomas: identification of mitotic index, hormone receptors and YWHAE-FAM22 translocation status as predictors of survival
Gremel G, Liew M, Hamzei F, Hardell E, Selling J, Ghaderi M, Stemme S, Pontén F, Carlson JW
Int J Cancer 2015 Apr 1;136(7):1608-18
PMID 25130488
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(10;17)(q22;p13) YWHAE/NUTM2B

External links

Mitelman database t(10;17)(q22;p13) [CaseList]    t(10;17)(q22;p13) [Transloc - MCList] YWHAE/NUTM2B [Fusion - MCList]
COSMIC[ YWHAE ]   [ NUTM2B ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(10;17)(q22;p13) YWHAE/NUTM2B
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Fri Feb 23 20:46:27 CET 2018


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