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t(10;19)(q26;q13) CIC/DUX4L10

Written08-2018Jean-Loup Huret, Philippe Dessen

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Atlas_Id 100428
Phylum Soft Tissues: Soft Tissues::
WHO/OMS Classification Soft Tissues
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Soft Tissues: Undifferentiated round cell sarcoma

Genes involved and Proteins

Gene NameCIC
Location 19q13.2

Gene NameDUX4L10
Location 10q26.3


High prevalence of CIC fusion with double-homeobox (DUX4) transcription factors in EWSR1-negative undifferentiated small blue round cell sarcomas
Italiano A, Sung YS, Zhang L, Singer S, Maki RG, Coindre JM, Antonescu CR
Genes Chromosomes Cancer 2012 Mar;51(3):207-18
PMID 22072439

Translocations implicated (Data extracted from papers in the Atlas)

 t(10;19)(q26;q13) CIC/DUX4L10

External links

Mitelman database t(10;19)(q26;q13) [Fusion]     t(10;19)(q26;q13) [Cytogenetics Case]
COSMIC[ CIC ]   [ DUX4L10 ]
Disease databaset(10;19)(q26;q13) CIC/DUX4L10
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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