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INTS4/GAB2 (11q14)

Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 100796
Phylum Female organs: Breast::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Breast: Adenocarcinoma

Genes involved and Proteins

Gene NameINTS4
Location 11q14.1

Gene NameGAB2
Location 11q14.1

Bibliography

Complex landscapes of somatic rearrangement in human breast cancer genomes
Stephens PJ, McBride DJ, Lin ML, Varela I, Pleasance ED, Simpson JT, Stebbings LA, Leroy C, Edkins S, Mudie LJ, Greenman CD, Jia M, Latimer C, Teague JW, Lau KW, Burton J, Quail MA, Swerdlow H, Churcher C, Natrajan R, Sieuwerts AM, Martens JW, Silver DP, Langerød A, Russnes HE, Foekens JA, Reis-Filho JS, van 't Veer L, Richardson AL, Børresen-Dale AL, Campbell PJ, Futreal PA, Stratton MR
Nature 2009 Dec 24;462(7276):1005-10
PMID 20033038
 
The landscape and therapeutic relevance of cancer-associated transcript fusions
Yoshihara K, Wang Q, Torres-Garcia W, Zheng S, Vegesna R, Kim H, Verhaak RG
Oncogene 2015 Sep 10;34(37):4845-54
PMID 25500544
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(11;11)(q14;q14) INTS4/GAB2

External links

Mitelman database t(11;11)(q14;q14) [CaseList]     t(11;11)(q14;q14) [Transloc - MCList]   INTS4/GAB2 Fusion - MCList]
COSMIC[ INTS4 ]   [ GAB2 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaseINTS4/GAB2 (11q14)
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Fri Oct 5 17:33:22 CEST 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.