| Written | 08-2018 | Jean-Loup Huret, Philippe Dessen |
| Identity |
| Atlas_Id | 100796 |
| Phylum | Female organs: Breast:: |
| WHO/OMS Classification | Female organs |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Breast: Adenocarcinoma |
| Genes involved and Proteins |
| Gene Name | INTS4 |
| Location | 11q14.1 |
| Gene Name | GAB2 |
| Location | 11q14.1 |
| Bibliography |
| Complex landscapes of somatic rearrangement in human breast cancer genomes |
| Stephens PJ, McBride DJ, Lin ML, Varela I, Pleasance ED, Simpson JT, Stebbings LA, Leroy C, Edkins S, Mudie LJ, Greenman CD, Jia M, Latimer C, Teague JW, Lau KW, Burton J, Quail MA, Swerdlow H, Churcher C, Natrajan R, Sieuwerts AM, Martens JW, Silver DP, Langerød A, Russnes HE, Foekens JA, Reis-Filho JS, van 't Veer L, Richardson AL, Børresen-Dale AL, Campbell PJ, Futreal PA, Stratton MR |
| Nature 2009 Dec 24;462(7276):1005-10 |
| PMID 20033038 |
| The landscape and therapeutic relevance of cancer-associated transcript fusions |
| Yoshihara K, Wang Q, Torres-Garcia W, Zheng S, Vegesna R, Kim H, Verhaak RG |
| Oncogene 2015 Sep 10;34(37):4845-54 |
| PMID 25500544 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| t(11;11)(q14;q14) INTS4/GAB2 | |
| External links |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Thu Feb 14 18:05:56 CET 2019 |
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