Atlas of Genetics and Cytogenetics in Oncology and Haematology

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t(11;15)(q21;q26) CRTC3::MAML2

(Note : for Links provided by Atlas : click)


Atlas_Id 100933
Phylum Head and Neck: Salivary gland::
WHO/OMS Classification Head and Neck
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Salivary gland: Mucoepidermoid carcinoma

Genes involved and Proteins

Gene NameCRTC3
Location 15q26.1

Gene NameMAML2
Location 11q21


A new type of MAML2 fusion in mucoepidermoid carcinoma
Fehr A, Röser K, Heidorn K, Hallas C, Löning T, Bullerdiek J
Genes Chromosomes Cancer 2008 Mar;47(3):203-6
PMID 18050304
Clinicopathological significance of the CRTC3-MAML2 fusion transcript in mucoepidermoid carcinoma
Nakayama T, Miyabe S, Okabe M, Sakuma H, Ijichi K, Hasegawa Y, Nagatsuka H, Shimozato K, Inagaki H
Mod Pathol 2009 Dec;22(12):1575-81
PMID 19749740
Impact of CRTC1/3-MAML2 fusions on histological classification and prognosis of mucoepidermoid carcinoma
Okumura Y, Miyabe S, Nakayama T, Fujiyoshi Y, Hattori H, Shimozato K, Inagaki H
Histopathology 2011 Jul;59(1):90-7
PMID 21668476
Clinicopathological significance of MAML2 gene split in mucoepidermoid carcinoma
Noda H, Okumura Y, Nakayama T, Miyabe S, Fujiyoshi Y, Hattori H, Shimozato K, Inagaki H
Cancer Sci 2013 Jan;104(1):85-92
PMID 23035786

Translocations implicated (Data extracted from papers in the Atlas)

 t(11;15)(q21;q26) CRTC3/MAML2

External links

Mitelman database t(11;15)(q21;q26) [CaseList]     t(11;15)(q21;q26) [Transloc - MCList]   CRTC3/MAML2 Fusion - MCList]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(11;15)(q21;q26) CRTC3::MAML2
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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indexed on : Tue Oct 12 15:00:54 CEST 2021

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