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t(12;12)(q13;q23) PCBP2/UHRF1BP1L

Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 101284
Phylum Nervous system: Central Nervous system::
WHO/OMS Classification Nervous system
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Central Nervous system: Astrocytoma, grade III-IV/Glioblastoma

Genes involved and Proteins

Gene NamePCBP2
Location 12q13.13

Gene NameUHRF1BP1L
Location 12q23.1

Bibliography

A survey of intragenic breakpoints in glioblastoma identifies a distinct subset associated with poor survival
Zheng S, Fu J, Vegesna R, Mao Y, Heathcock LE, Torres-Garcia W, Ezhilarasan R, Wang S, McKenna A, Chin L, Brennan CW, Yung WK, Weinstein JN, Aldape KD, Sulman EP, Chen K, Koul D, Verhaak RG
Genes Dev 2013 Jul 1;27(13):1462-72
PMID 23796897
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(12;12)(q13;q23) PCBP2/UHRF1BP1L

External links

Mitelman database t(12;12)(q13;q23) [CaseList]     t(12;12)(q13;q23) [Transloc - MCList]   PCBP2/UHRF1BP1L Fusion - MCList]
COSMIC[ PCBP2 ]   [ UHRF1BP1L ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(12;12)(q13;q23) PCBP2/UHRF1BP1L
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Wed Nov 28 16:56:36 CET 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.