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t(12;12)(q15;q21) NUP107/LGR5

Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 101333
Phylum Soft Tissues: Soft Tissues::
WHO/OMS Classification Soft Tissues
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Soft Tissues: Liposarcoma, dedifferentiated

Genes involved and Proteins

Gene NameNUP107
Location 12q15

Gene NameLGR5
Location 12q21.1

Bibliography

Identification of a novel, recurrent HEY1-NCOA2 fusion in mesenchymal chondrosarcoma based on a genome-wide screen of exon-level expression data
Wang L, Motoi T, Khanin R, Olshen A, Mertens F, Bridge J, Dal Cin P, Antonescu CR, Singer S, Hameed M, Bovee JV, Hogendoorn PC, Socci N, Ladanyi M
Genes Chromosomes Cancer 2012 Feb;51(2):127-39
PMID 22034177
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(12;12)(q15;q21) NUP107/LGR5

External links

Mitelman database t(12;12)(q15;q21) [CaseList]     t(12;12)(q15;q21) [Transloc - MCList]   NUP107/LGR5 Fusion - MCList]
COSMIC[ NUP107 ]   [ LGR5 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(12;12)(q15;q21) NUP107/LGR5
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Wed Nov 28 16:56:50 CET 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.