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t(12;12)(q15;q21) ZFC3H1/MDM2

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 108109
Phylum Bones::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Bones:Osteosarcoma, NOS

Genes involved and Proteins

Gene NameZFC3H1
Location 12q21.1

Gene NameMDM2
Location 12q15

Bibliography

Recurrent LRP1-SNRNP25 and KCNMB4-CCND3 fusion genes promote tumor cell motility in human osteosarcoma
Yang J, Annala M, Ji P, Wang G, Zheng H, Codgell D, Du X, Fang Z, Sun B, Nykter M, Chen K, Zhang W
J Hematol Oncol 2014 Oct 10;7:76
PMID 25300797
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(12;12)(q15;q21) ZFC3H1/MDM2

External links

Mitelman database t(12;12)(q15;q21) [CaseList]     t(12;12)(q15;q21) [Transloc - MCList]   ZFC3H1/MDM2 Fusion - MCList]
COSMIC[ ZFC3H1 ]   [ MDM2 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(12;12)(q15;q21) ZFC3H1/MDM2
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Fri Jun 22 18:11:15 CEST 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.