t(12;16)(q13;p13) LRP1/SNRNP25

0000-00-00   Jean-Loup Huret , Philippe Dessen 

(Note: the fusion was discovered by NGS. Many chromosome rearrangement mechanisms such as translocation, inversion,deletion or complex rearrangement may lead to the same fusion)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute

Summary

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Genes Involved and Proteins

Gene name

LRP1

Location

12q13.3

Gene name

SNRNP25

Location

16p13.3

Highly cited references

Pubmed IDYearTitleCitations
267385042016Roles of low-density lipoprotein receptor-related protein 1 in tumors.22
253007972014Recurrent LRP1-SNRNP25 and KCNMB4-CCND3 fusion genes promote tumor cell motility in human osteosarcoma.14
254181922014Investigation of osteosarcoma genomics and its impact on targeted therapy: an international collaboration to conquer human osteosarcoma.5

Bibliography

Pubmed IDLast YearTitleAuthors
253007972014Recurrent LRP1-SNRNP25 and KCNMB4-CCND3 fusion genes promote tumor cell motility in human osteosarcoma.Yang J et al

Citation

Jean-Loup Huret ; Philippe Dessen

t(12;16)(q13;p13) LRP1/SNRNP25

Atlas Genet Cytogenet Oncol Haematol. 0000-00-00

Online version: http://atlasgeneticsoncology.org/solid-tumor/101495/t(12;16)(q13;p13)-lrp1-snrnp25