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t(14;18)(q32;q21) IGH/MALT1

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)


Atlas_Id 109421
Phylum Head and Neck: Eye::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

Clinics and Pathology

Disease Head and Neck: Eye:Extranodal marginal zone B-cell lymphoma

Genes involved and Proteins

Gene NameIGH
Location 14q32.33

Gene NameMALT1
Location 18q21.32


T(14;18)(q32;q21) involving IGH and MALT1 is a frequent chromosomal aberration in MALT lymphoma
Streubel B, Lamprecht A, Dierlamm J, Cerroni L, Stolte M, Ott G, Raderer M, Chott A
Blood 2003 Mar 15;101(6):2335-9
PMID 12406890
MALT1 is deregulated by both chromosomal translocation and amplification in B-cell non-Hodgkin lymphoma
Sanchez-Izquierdo D, Buchonnet G, Siebert R, Gascoyne RD, Climent J, Karran L, Marin M, Blesa D, Horsman D, Rosenwald A, Staudt LM, Albertson DG, Du MQ, Ye H, Marynen P, Garcia-Conde J, Pinkel D, Dyer MJ, Martinez-Climent JA
Blood 2003 Jun 1;101(11):4539-46
PMID 12560219
Translocations t(11;18)(q21;q21) and t(14;18)(q32;q21) are the main chromosomal abnormalities involving MLT/MALT1 in MALT lymphomas
Murga Penas EM, Hinz K, Röser K, Copie-Bergman C, Wlodarska I, Marynen P, Hagemeijer A, Gaulard P, Löning T, Hossfeld DK, Dierlamm J
Leukemia 2003 Nov;17(11):2225-9
PMID 12931213

Translocations implicated (Data extracted from papers in the Atlas)

 t(14;18)(q32;q21) IGH/MALT1

External links

Mitelman database t(14;18)(q32;q21) [CaseList]    t(14;18)(q32;q21) [Transloc - MCList] IGH/MALT1 [Fusion - MCList]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(14;18)(q32;q21) IGH/MALT1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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indexed on : Fri Feb 23 20:51:41 CET 2018

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