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LEO1/SLC12A1 (15q21)

Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 101949
Phylum Nervous system: Central Nervous system::
WHO/OMS Classification Nervous system
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Central Nervous system: Astrocytoma, grade III-IV/Glioblastoma

Genes involved and Proteins

Gene NameLEO1
Location 15q21.2

Gene NameSLC12A1
Location 15q21.1

Bibliography

Integrated genomic profiling identifies candidate genes implicated in glioma-genesis and a novel LEO1-SLC12A1 fusion gene
Bralten LB, Kloosterhof NK, Gravendeel LA, Sacchetti A, Duijm EJ, Kros JM, van den Bent MJ, Hoogenraad CC, Sillevis Smitt PA, French PJ
Genes Chromosomes Cancer 2010 Jun;49(6):509-17
PMID 20196086
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(15;15)(q21;q21) LEO1/SLC12A1

External links

Mitelman database t(15;15)(q21;q21) [CaseList]     t(15;15)(q21;q21) [Transloc - MCList]   LEO1/SLC12A1 Fusion - MCList]
COSMIC[ LEO1 ]   [ SLC12A1 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaseLEO1/SLC12A1 (15q21)
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Wed Nov 7 18:21:17 CET 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.