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t(17;19)(p13;q13) KMT2B/GPS2

Written08-2018Jean-Loup Huret, Philippe Dessen

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Atlas_Id 102892
Phylum Soft Tissues: Soft Tissues::
WHO/OMS Classification Soft Tissues
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Soft Tissues: Soft tissue tumor, special type

Genes involved and Proteins

Gene NameKMT2B
Location 19q13.12

Gene NameGPS2
Location 17p13.1


Identification of an MLL4-GPS2 fusion as an oncogenic driver of undifferentiated spindle cell sarcoma in a child
O'Meara E, Stack D, Phelan S, McDonagh N, Kelly L, Sciot R, Debiec-Rychter M, Morris T, Cochrane D, Sorensen P, O'Sullivan MJ
Genes Chromosomes Cancer 2014 Dec;53(12):991-8
PMID 25139254

Translocations implicated (Data extracted from papers in the Atlas)

 t(17;19)(p13;q13) KMT2B/GPS2

External links

Mitelman database t(17;19)(p13;q13) [Fusion]     t(17;19)(p13;q13) [Cytogenetics Case]
COSMIC[ KMT2B ]   [ GPS2 ]
Disease databaset(17;19)(p13;q13) KMT2B/GPS2
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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indexed on : Mon Jul 13 11:27:01 CEST 2020

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