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t(17;20)(q12;q11) TRPC4AP/MRPL45

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 104253
Phylum Female organs: Breast::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Female organs: Breast:Adenocarcinoma

Genes involved and Proteins

Gene NameTRPC4AP
Location 20q11.22

Gene NameMRPL45
Location 17q12

Bibliography

A novel bioinformatics pipeline for identification and characterization of fusion transcripts in breast cancer and normal cell lines
Asmann YW, Hossain A, Necela BM, Middha S, Kalari KR, Sun Z, Chai HS, Williamson DW, Radisky D, Schroth GP, Kocher JP, Perez EA, Thompson EA
Nucleic Acids Res 2011 Aug;39(15):e100
PMID 21622959
 
Gene fusions associated with recurrent amplicons represent a class of passenger aberrations in breast cancer
Kalyana-Sundaram S, Shankar S, Deroo S, Iyer MK, Palanisamy N, Chinnaiyan AM, Kumar-Sinha C
Neoplasia 2012 Aug;14(8):702-8
PMID 22952423
 
Reanalysis of RNA-sequencing data reveals several additional fusion genes with multiple isoforms
Kangaspeska S, Hultsch S, Edgren H, Nicorici D, Murumägi A, Kallioniemi O
PLoS One 2012;7(10):e48745
PMID 23119097
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(17;20)(q12;q11) TRPC4AP/MRPL45

External links

Mitelman database t(17;20)(q12;q11) [CaseList]     t(17;20)(q12;q11) [Transloc - MCList]   TRPC4AP/MRPL45 Fusion - MCList]
COSMIC[ TRPC4AP ]   [ MRPL45 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(17;20)(q12;q11) TRPC4AP/MRPL45
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Fri Jun 22 18:17:15 CEST 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.