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t(18;18)(q21;q21) SMAD4/RAX

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 101025
Phylum Nervous system: Central Nervous system::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Nervous system: Central Nervous system:Astrocytoma, grade III-IV/Glioblastoma

Genes involved and Proteins

Gene NameSMAD4
Location 18q21.2

Gene NameRAX
Location Xq27.3

Bibliography

The integrated landscape of driver genomic alterations in glioblastoma
Frattini V, Trifonov V, Chan JM, Castano A, Lia M, Abate F, Keir ST, Ji AX, Zoppoli P, Niola F, Danussi C, Dolgalev I, Porrati P, Pellegatta S, Heguy A, Gupta G, Pisapia DJ, Canoll P, Bruce JN, McLendon RE, Yan H, Aldape K, Finocchiaro G, Mikkelsen T, Privé GG, Bigner DD, Lasorella A, Rabadan R, Iavarone A
Nat Genet 2013 Oct;45(10):1141-9
PMID 23917401
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(18;18)(q21;q21) SMAD4/RAX

External links

Mitelman database t(18;18)(q21;q21) [CaseList]     t(18;18)(q21;q21) [Transloc - MCList]   SMAD4/RAX Fusion - MCList]
COSMIC[ SMAD4 ]   [ RAX ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(18;18)(q21;q21) SMAD4/RAX
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Fri Jun 22 18:17:40 CEST 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.