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t(18;20)(q11;q15) TMEM241/HM13

Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 103081
Phylum Female organs: Breast::
WHO/OMS Classification Female organs
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Breast: Adenocarcinoma

Genes involved and Proteins

Gene NameTMEM241
Location 18q11.2

Gene NameHM13
Location 20q11.21

Bibliography

Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer
Robinson DR, Kalyana-Sundaram S, Wu YM, Shankar S, Cao X, Ateeq B, Asangani IA, Iyer M, Maher CA, Grasso CS, Lonigro RJ, Quist M, Siddiqui J, Mehra R, Jing X, Giordano TJ, Sabel MS, Kleer CG, Palanisamy N, Natrajan R, Lambros MB, Reis-Filho JS, Kumar-Sinha C, Chinnaiyan AM
Nat Med 2011 Nov 20;17(12):1646-51
PMID 22101766
 
Gene fusions associated with recurrent amplicons represent a class of passenger aberrations in breast cancer
Kalyana-Sundaram S, Shankar S, Deroo S, Iyer MK, Palanisamy N, Chinnaiyan AM, Kumar-Sinha C
Neoplasia 2012 Aug;14(8):702-8
PMID 22952423
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(18;20)(q11;q15) TMEM241/HM13

External links

Mitelman database t(18;20)(q11;q15) [CaseList]     t(18;20)(q11;q15) [Transloc - MCList]   TMEM241/HM13 Fusion - MCList]
COSMIC[ TMEM241 ]   [ HM13 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(18;20)(q11;q15) TMEM241/HM13
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Wed Nov 28 17:05:04 CET 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.