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t(19;19)(p13;p13) SMARCA4/CARM1

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 103825
Phylum Female organs: Breast::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Female organs: Breast:Adenocarcinoma

Genes involved and Proteins

Gene NameSMARCA4
Location 19p13.2

Gene NameCARM1
Location 19p13.2

Bibliography

Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer
Robinson DR, Kalyana-Sundaram S, Wu YM, Shankar S, Cao X, Ateeq B, Asangani IA, Iyer M, Maher CA, Grasso CS, Lonigro RJ, Quist M, Siddiqui J, Mehra R, Jing X, Giordano TJ, Sabel MS, Kleer CG, Palanisamy N, Natrajan R, Lambros MB, Reis-Filho JS, Kumar-Sinha C, Chinnaiyan AM
Nat Med 2011 Nov 20;17(12):1646-51
PMID 22101766
 
RNA-Seq mapping and detection of gene fusions with a suffix array algorithm
Sakarya O, Breu H, Radovich M, Chen Y, Wang YN, Barbacioru C, Utiramerur S, Whitley PP, Brockman JP, Vatta P, Zhang Z, Popescu L, Muller MW, Kudlingar V, Garg N, Li CY, Kong BS, Bodeau JP, Nutter RC, Gu J, Bramlett KS, Ichikawa JK, Hyland FC, Siddiqui AS
PLoS Comput Biol 2012;8(4):e1002464
PMID 22496636
 
Reanalysis of RNA-sequencing data reveals several additional fusion genes with multiple isoforms
Kangaspeska S, Hultsch S, Edgren H, Nicorici D, Murumägi A, Kallioniemi O
PLoS One 2012;7(10):e48745
PMID 23119097
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(19;19)(p13;p13) SMARCA4/CARM1

External links

Mitelman database t(19;19)(p13;p13) [CaseList]     t(19;19)(p13;p13) [Transloc - MCList]   SMARCA4/CARM1 Fusion - MCList]
COSMIC[ SMARCA4 ]   [ CARM1 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(19;19)(p13;p13) SMARCA4/CARM1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Fri Jun 22 18:18:06 CEST 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.