MYCL (MYCL proto-oncogene, bHLH transcription factor)

2003-02-01  

Identity

HGNC
MYCL
LOCATION
1p34.2
LOCUSID
4610
ALIAS
L-Myc,LMYC,MYCL1,bHLHe38
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4610
MIM: 164850
HGNC: 7555
Ensembl: ENSG00000116990

Variants:

dbSNP: 4610
ClinVar: 4610
TCGA: ENSG00000116990
COSMIC: MYCL

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000116990ENST00000372815P12524
ENSG00000116990ENST00000372816P12524
ENSG00000116990ENST00000397332P12524
ENSG00000116990ENST00000450953E9PQS5

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
190205492009Array-CGH reveals recurrent genomic changes in Merkel cell carcinoma including amplification of L-Myc.39
128837492003Genetic polymorphisms and susceptibility to esophageal cancer among Chinese population (review).38
216768852011Genetic variation in an miRNA-1827 binding site in MYCL1 alters susceptibility to small-cell lung cancer.28
121692062002MYCL1, FHIT, SPARC, p16(INK4) and TP53 genes associated to lung cancer in idiopathic pulmonary fibrosis.20
200958542010Novel breast cancer risk alleles and interaction with ionizing radiation among U.S. radiologic technologists.16
171450942007Ethnic differences in frequencies of gene polymorphisms in the MYCL1 region and modulation of lung cancer patients' survival.11
171450942007Ethnic differences in frequencies of gene polymorphisms in the MYCL1 region and modulation of lung cancer patients' survival.11
195361702009Cell proliferation-related genetic polymorphisms and gastric cancer risk: systematic review and meta-analysis.6
233490192013Association of polymorphisms and haplotype in the region of TRIT1, MYCL1 and MFSD2A with the risk and clinicopathological features of gastric cancer in a southeast Chinese population.6
119556462002Association of L-myc polymorphism with lung cancer susceptibility and prognosis in relation to age-selected controls and stratified cases.5

Citation

Dessen P

MYCL (MYCL proto-oncogene, bHLH transcription factor)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/170/mycl-(mycl-proto-oncogene-bhlh-transcription-factor)