RRAD (RRAD, Ras related glycolysis inhibitor and calcium channel regulator)

2003-02-01  

Identity

HGNC
RRAD
LOCATION
16q22.1
LOCUSID
6236
ALIAS
RAD,RAD1,REM3

Other Information

Locus ID:

NCBI: 6236
MIM: 179503
HGNC: 10446
Ensembl: ENSG00000166592

Variants:

dbSNP: 6236
ClinVar: 6236
TCGA: ENSG00000166592
COSMIC: RRAD

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166592ENST00000299759P55042
ENSG00000166592ENST00000299759A0A024R6X0
ENSG00000166592ENST00000420652P55042
ENSG00000166592ENST00000420652A0A024R6X0
ENSG00000166592ENST00000566577J3KSM6
ENSG00000166592ENST00000568915J3KRG9

Expression (GTEx)

0
50
100
150
200
250
300
350
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
369794122023Friend or Foe: Regulation, Downstream Effectors of RRAD in Cancer.5
369794122023Friend or Foe: Regulation, Downstream Effectors of RRAD in Cancer.5
340016162021Reconstitution of β-adrenergic regulation of Ca(V)1.2: Rad-dependent and Rad-independent protein kinase A mechanisms.10
340016162021Reconstitution of β-adrenergic regulation of Ca(V)1.2: Rad-dependent and Rad-independent protein kinase A mechanisms.10
303916752019Pan-senescence transcriptome analysis identified RRAD as a marker and negative regulator of cellular senescence.14
311148542019RRAD mutation causes electrical and cytoskeletal defects in cardiomyocytes derived from a familial case of Brugada syndrome.22
318576162019RRAD expression in gastric and colorectal cancer with peritoneal carcinomatosis.5
303916752019Pan-senescence transcriptome analysis identified RRAD as a marker and negative regulator of cellular senescence.14
311148542019RRAD mutation causes electrical and cytoskeletal defects in cardiomyocytes derived from a familial case of Brugada syndrome.22
318576162019RRAD expression in gastric and colorectal cancer with peritoneal carcinomatosis.5
265464382016RRAD inhibits aerobic glycolysis, invasion, and migration and is associated with poor prognosis in hepatocellular carcinoma.16
265464382016RRAD inhibits aerobic glycolysis, invasion, and migration and is associated with poor prognosis in hepatocellular carcinoma.16
258933812015RRAD inhibits the Warburg effect through negative regulation of the NF-κB signaling.23
263446872015Brahma-related gene 1 inhibits proliferation and migration of human aortic smooth muscle cells by directly up-regulating Ras-related associated with diabetes in the pathophysiologic processes of aortic dissection.14
258933812015RRAD inhibits the Warburg effect through negative regulation of the NF-κB signaling.23

Citation

Dessen P

RRAD (RRAD, Ras related glycolysis inhibitor and calcium channel regulator)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/277/img/favicon/js/lib/bootstrap.min.js