Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3195
MIM: 186770
HGNC: 5056
Ensembl: ENSG00000107807
Variants:
dbSNP: 3195
ClinVar: 3195
TCGA: ENSG00000107807
COSMIC: TLX1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000107807 | ENST00000370196 | P31314 |
| ENSG00000107807 | ENST00000463716 | G3V1B7 |
| ENSG00000107807 | ENST00000467928 | P31314 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Transcriptional misregulation in cancer | KEGG | ko05202 |
| Transcriptional misregulation in cancer | KEGG | hsa05202 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32488880 | 2020 | Association of TLX1 gene polymorphisms with the risk of acute lymphoblastic leukemia and B lineage acute lymphoblastic leukemia in Han Chinese children. | 1 |
| 32488880 | 2020 | Association of TLX1 gene polymorphisms with the risk of acute lymphoblastic leukemia and B lineage acute lymphoblastic leukemia in Han Chinese children. | 1 |
| 29555975 | 2018 | Orphan nuclear receptor TLX contributes to androgen insensitivity in castration-resistant prostate cancer via its repression of androgen receptor transcription. | 16 |
| 29954933 | 2018 | A comprehensive inventory of TLX1 controlled long non-coding RNAs in T-cell acute lymphoblastic leukemia through polyA+ and total RNA sequencing. | 10 |
| 30107177 | 2018 | Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia. | 31 |
| 29555975 | 2018 | Orphan nuclear receptor TLX contributes to androgen insensitivity in castration-resistant prostate cancer via its repression of androgen receptor transcription. | 16 |
| 29954933 | 2018 | A comprehensive inventory of TLX1 controlled long non-coding RNAs in T-cell acute lymphoblastic leukemia through polyA+ and total RNA sequencing. | 10 |
| 30107177 | 2018 | Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia. | 31 |
| 28351398 | 2017 | Genome-wide methylation analysis identifies a core set of hypermethylated genes in CIMP-H colorectal cancer. | 24 |
| 28674422 | 2017 | Increased methylation and decreased expression of homeobox genes TLX1, HOXA10 and DLX5 in human placenta are associated with trophoblast differentiation. | 10 |
| 28351398 | 2017 | Genome-wide methylation analysis identifies a core set of hypermethylated genes in CIMP-H colorectal cancer. | 24 |
| 28674422 | 2017 | Increased methylation and decreased expression of homeobox genes TLX1, HOXA10 and DLX5 in human placenta are associated with trophoblast differentiation. | 10 |
| 24001773 | 2013 | G-quadruplex structures formed at the HOX11 breakpoint region contribute to its fragility during t(10;14) translocation in T-cell leukemia. | 23 |
| 24001773 | 2013 | G-quadruplex structures formed at the HOX11 breakpoint region contribute to its fragility during t(10;14) translocation in T-cell leukemia. | 23 |
| 22366949 | 2012 | Reverse engineering of TLX oncogenic transcriptional networks identifies RUNX1 as tumor suppressor in T-ALL. | 80 |
Citation
Dessen P
TLX1 (T cell leukemia homeobox 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/31/ang-(angiogenin-ribonuclease-rnase-a-family-5)
